David Schaffer Professor, Department of Bioengineering and Chemical Engineering and Helen Wills Neuroscience Institute Chemist Faculty, Lawrence Berkeley National Lab 274 Stanley Hall mailcode: MC 3220 (510) 643-5963 fax: (510) 642-4778 This e-mail address is being protected from spambots. You need JavaScript enabled to view it http://www.cchem.berkeley.edu/schaffer/

Joined the UC Berkeley Faculty in 1999

Research Interests

Stem cell engineering, Gene delivery and therapy, Gene network biology

Education

1993    B.S., Stanford University, Chemical Engineering
1998    Ph.D., Massachusetts Institute of Technology, Chemical Engineering

Major Awards

2008               Robert W. Vaughan Lectureship, California Institute of Technology

2006               American Chemical Society Biochemical Technology Division Young Investigator Award

2005               Van Ness Award Lectureship, Rensselaer Polytechnic Institute

2003               Departmental Citation for Excellence in Teaching

2002               Technology Review Magazine "Top 100 Innovator Under 35"

2002               American Institute of Chemical Engineers (NorCal) Excellence in Teaching Award

2001               Hellman Family Faculty Award

2001-2004     Whitaker Foundation Biomedical Engineering Research Award (Young Investigator)

2001-2006     National Science Foundation CAREER Award

2001-2004     Office of Naval Research Young Investigator

2000               Biomedical Engineering Society Rita Shaffer Young Investigator Award

1999               Regents' Junior Faculty Award

1998               NIH Postdoctoral Fellowship (Individual NRSA)

1997               MIT Outstanding Seminar Award

1993               National Science Foundation Graduate Fellowship (declined)

1993               Whitaker Foundation Graduate Fellowship (declined)

1993-1998       Fannie and John Hertz Foundation Graduate Fellowship

Professional Experience

1999-2005     Assistant Professor, Department of Chemical Engineering & Helen Wills Neuroscience Institute, U.C. Berkeley

2005-2007     Associate Professor, Department of Chemical Engineering & Helen Wills Neuroscience Institute, U.C. Berkeley

2005-            Chemist Scientist Faculty, Physical Biosciences Division, Lawrence Berkeley National Lab

2007-             Associate Director, Berkeley Stem Cell Center

2007-             Professor, Department of Chemical Engineering, Department of Bioengineering, & Helen Wills Neuroscience Institute, U.C. Berkeley

Selected Publications

    Lai, K, B.K. Kaspar, F.H. Gage, and D.V. Schaffer (2003) “Sonic Hedgehog Regulates Adult Neural Progenitor Proliferation in Vitro and in Vivo.” Nature Neuroscience, 6(1): 21-27.
    Maheshri, N. and D.V. Schaffer “Computational and Experimental Analysis of DNA Shuffling.” Proceedings of the National Academy of Sciences USA, 100:3071-3076.
    Weinberger, L.S., J.C. Burnett, J.E. Toettcher, A.P. Arkin, and D.V. Schaffer (2005) “Stochastic Gene Expression in a Lentiviral Feedback Loop: HIV-1 Tat Expression Drives Phenotypic Diversity.” Cell, 122:169-182.
    Maheshri, N., J.T. Koerber, B. Kaspar, and D.V. Schaffer (2006) “Directed Evolution of Adeno-Associated Virus Yields Enhanced Gene Delivery Vectors.”  Nature Biotechnology, 24:198-204.
    Peltier, J., A. O’Neill, and D.V. Schaffer (2007) “PI3K/Akt and CREB Regulate Adult Neural Hippocampal Progenitor Proliferation and Differentiation.” Developmental Neurobiology, 67:1348-1361.